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Zepbound Weight Loss Results at 72 Weeks by Dose Mounjaro HbA1c Results for Type 2 Diabetes In the Mounjaro prescribing information, SURPASS-1 (NCT03954834) was a 40-week trial in adults with type 2 diabetes whose blood sugar was not adequately controlled with diet and exercise alone

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In developing countries, the availability of semaglutide might be limited due to its high cost, while orlistat may be more commonly accessible

By reducing glucagon secretion when glucose levels are elevated, GLP-1 agonists help decrease hepatic glucose output, further improving overall glucose homeostasis